Axis-Shield PoC - Cardiovascular Disease

Cardiovascular disease is endemic in the western world, costing millions of lives every single year. Axis-Shield PoC are developing tests that can be used as an indication for the risk of developing cardiovascular disease, or to monitor drugs used for anticoagulation therapy.

Acute blood clots

Elevated levels of fibrin degradation products (D-dimer) are indicative of the presence of a significant blood clot. Blood clots form when long strands of fibrin attach to each other to form a clot. Meanwhile, the cell walls initiate a mechanism that can dissolve the coagulated blood, and the marker D-dimer is one of the products released during this process. Formation of blood clots may be induced by a variety of causes including deep venous thrombosis or pulmonary embolism.

Anticoagulation therapy

Several conditions such as myocardial infarction, venous thrombosis, pulmonary embolism, hip surgery, valvular heart disease etc. initiate the use of anticoagulation therapy. To ensure correct dosage of the preferred drug, Thrombotest or Nycotest PT can be used to monitor treatment with anticoagulants.